First successful IVF experience
In July 1987, the famous "Louise Brown", the first IVF baby, was born in England. One of the first doctors to make this treatment successful, Dr.Steptoe and Dr. Edwards made his mark in history.
After this success, ovulation treatments continued to be developed and advanced. Hormones, which were used for this purpose, began to develop between 1979 and 1980.
The original use of IVF treatment was in cases where the tubes were clogged, and this thought developed further in the minds, and the application areas and reasons increased day by day.
* First microinjection (ICSI) application
The path covered in the first microinjection (ICSI) application was passed in 1996.
The success rate of ICSI, that is, in vitro fertilization with microinjection, has increased even more, and a great distance has been covered in male infertility problems, which were previously ignored.
Today, there are tens of thousands of babies born with the ICSI method around the world.
There are many scientific studies on the IVF treatment method every year. As these works are carried out, they continue in a hopeful and morale way.
* Expectations in the possible development of IVF treatment methods in the future.
There are always good developments regarding in vitro fertilization methods. PGD (Preimplantation genetic diagnosis) methods are becoming common.
Genetic testing, better laboratory mediums and environments, better evaluations of sperm quality, and IVF significantly increase the rate of pregnancy and delivery.
* First studies of infertility treatment
Studies on infertility in the world date back to a long time ago. Studies on animals started 150 years ago.
The first human oocyte (egg) studies started in 1939 and the hormones developed for treatment were successfully developed until the birth of the first IVF, Louise Brown.
* Infertility and IVF
Hippocrates (460-337 BC) emphasized the importance of the opening of the uterus and tuba in getting pregnant and also the place where sperms are found in reproduction.
Another scientist of this period, Aristotle (384-332 BC), explained his thoughts on reproductive function. Soranus was born in Ephesus and was one of the first to describe the fertile period. In vitro fertilization method research and efforts started with animals. Walter Heape conducted successful experiments on rabbits in 1890.
* Which new techniques have been implemented in IVF treatments today?
Artificial womb applications (Co-way of life: Co-occultur): Its usefulness is scientifically controversial.
Egg and embryo freezing processes (Freezing)
Making the embryo membrane thinner (Assisted Hatching)
IMSI technique in IVF treatments
Acupuncture applications to support IVF treatment
Preimplantation genetic diagnosis applications (PGD)
Targeting quality embryo selection with metabolomics technique
Genetic diagnostic methods with PGD and CGH
* Which stages have been determined as criteria in IVF treatments from history to the present?
In the first stage, the individuals who will be examined and treated will be evaluated.
In the second stage, stimulating the ovaries and providing opportunities for the egg to develop.
Collecting the eggs in the third stage,
In the fourth stage, fertilization is carried out,
Finally, the embryo is transferred to the mother's womb.
* What achievements have been developed since the first day of IVF?
From these developments until today, IVF treatment has achieved many successes. These recorded successes are maturing and hitting every day, and the success rates of the treatments are increased.
1983 First birth after embryo freezing (Trounson).
1984 Gamet First birth after intrafallopian transfer (gift) (Asch).
1986 First birth after ZIFT (Devroey) (15)
1986 First pregnancy after oocyte freezing (Chen).
1988 First pregnancy (Ng) after subzonal insemination (SUZI).
1990 First pregnancy after PGD (Handyside).
1992 Intracytoplasmic sperm injection (ICSI) (Palermo) (23)